Royal Air Force Typhoon jets have operated alongside French aircraft in a combined operation against an hidden munitions depot in Syria employed by the IS group, per a report from the UK's MoD.
The location, located using reconnaissance, was thought to be housing weapons and explosive materials, the announcement noted, and was situated in hills just above the historic site of Palmyra in the heart of Syria.
"Our aircraft utilized Paveway IV guided bombs to target a number of entry passages providing entry to the depot... initial indications indicate the target was engaged successfully," the ministry announced.
There was no sign of any civilian casualties in the strike conducted Saturday night and every plane involved returned safely, the defence officials confirmed.
The British jets were backed up by a Voyager aerial refuelling aircraft.
Daesh - referred to as the so-called Islamic State - enforced extremist governance over parts of Iraq and Syria before its territorial defeat in 2019.
"This strike shows British leadership, and resolve to stand shoulder to shoulder with our partners, to eliminate any re-emergence of Daesh and their dangerous and violent ideologies in the Middle East," the British Defence Secretary the Defence Secretary stated.
RAF aircraft have conducted patrols over Syria to "deter any attempted resurgence" of the group after its routing at the battle of Baghuz in the year 2019, the MoD reported.
"I want to thank the personnel of the UK armed forces who took part in this operation for their skill and their valour," Healey said. "Including them were numerous UK service members stationed over Christmas and New Year. This action, to remove militants who threaten our security, demonstrates how our armed forces are always on standby, all year round, ensuring Britain's security at home and strong abroad."
Last December, the United States armed forces carried out what it called a "massive strike" on Islamic State objectives in Syria, after an ambush resulted in the deaths of two US servicemembers and a local interpreter in Palmyra.
The U.N. reports IS still maintains between 5,000 and 7,000 fighters in Syria and Iraq.